Anaerobic brain abscess
Abstract
Background: Brain abscess remains a potentially fatal central nervous system (CNS) disease, especially in developing countries. Anaerobic abscess is difficult to diagnose because of cumbersome procedures associated with the isolation of anaerobes.
Materials and Methods: This is a hospital-based retrospective microbiological analysis of 430 brain abscess materials (purulent aspirates and/or tissue), for anaerobic organisms, that were received between 1987-2014, by the Microbiology Laboratory in our Institute.
Results: Culture showed growth of bacteria116/430(27%) of the cases of which anaerobes were isolated in 48/116(41.1%) of the cases. Peptostreptococcus (51.4 %), was the predominant organism isolated in four cases followed by Bacteroides and Peptococcus species.
Conclusion :Early diagnosis and det ction of these organisms would help in the appropriate management of these patients.
Das S K, Tiwari Divye Prakash, Sharma Vivek, Nath Gopal. Microbiological profile of brain abscess. World J Med Res 2013; 2:56-62.
Alvis Miranda H, Castellar-Leones SM, Elzain MA, Moscote-Salazar LR . Brain abscess: Current manage- ment. J Neurosci Rural Pract 2013;4(Suppl 1):S67-81.
Bernardini GL .Diagnosis and management of brain abscess and subdural empyema. Curr Neurol Neurosci Rep 2004;4: 448-456.
Lu CH, Chang WN, Lin YC, Tsai NW, Liliang PC, Su TM, et al. Bacterial brain abscess: microbiological features, epidemiological trends and therapeutic out- comes. QJM 2002;95:501-509.
Dogan M, Keskin F, Feyzioglu B, Baykan M, Ozdemir M, Kalkan E, et al . A case report of cerebellar abscess caused by Bacteroides fragilis. Am J Clinical Med Res 2013; 4: 48-50.
Rosenblum ML, Mampalam TJ, Pons VG. Controver- sies in the management of brain abscesses. Clin Neuro- surg 1986;33:603-632.
Sanders CV, Aldridge KE. Current antimicrobial ther- apy of anaerobic infections. Eur J Clin Microbiol Infect Dis 1992;11:999-1011.
Brook I .Anaerobic bacteria in upper respiratory tract and head and neck infections: microbiology and treat- ment. Anaerobe 2012;18:214-220.
Cox K, Al-Rawahi G, Kollmann T. Anaerobic brain abscess following chronic suppurative otitis media in a child from Uganda. Can J Infect Dis Med Microbiol 2009;20(3):e91-93.
Zhang C, Hu L, Wu X, Hu G, Ding X, Lu Y . A retro- spective study on the aetiology, management, and out- come of brain abscess in an 11-year, single-centre study from China. BMC Infect Dis 2014;14:311.
Tokatli A, Kanra G, Ayhan Z, Koçoglu T, Seçmeer G, Oran O. A cerebellar abscess caused by anaerobic and aerobic (mixed) microorganisms. Mikrobiyol Bul 1984;18:208-212.
Chakraborty RN, Bidwai PS, Kak VK, Banarjee AK, Khattri HN, Sapru RP, et al. Brain abscess in cyanotic congenital heart disease. Indian Heart J 1989;41:190-193.
Kagawa M, Takeshita M, Yato S, Kitamura K . Brain abscess in congenital cyanotic heart disease. J Neuro- surg 1983; 58:913-917.
Muzumdar D, Jhawar S, Goel A. Brain abscess: an overview. Int J Surg 2011;9:136-144.
Lumbiganon P, Chaikitpinyo A . Antibiotics for brain abscesses in people with cyanotic congenital heart dis-ease. Cochrane Database Syst Rev 2013;3: CD004469.
Prusty GK. Brain abscesses in cyanotic heart disease.Indian J Pediatr 1993;60:43-51.
Mehnaz A, Syed AU, Saleem AS, Khalid CN. Clinical features and outcome of cerebral abscess in congenital heart disease. J Ayub Med Coll Abbottabad 2006;18:21-24.
Abrar A Wani, Altaf U Ramzan, Nayil K Malik, Ash- ish Kumar, Anil Dhar, et al. Brain abscess complicating hemorrhagic contusion in a case of closed head injury: Case report. IJNT 2011;8: 49-50.
Han S, Lim DJ, Chung YG, Cho TH, Lim SJ, Kim WJ, et al . The multiple brain abscesses associated with con- genital pulmonary arteriovenous malformations: a case report. J Korean Med Sci 2002;17:407-411.
Muzumdar D .Central nervous system infections and the neurosurgeon: a perspective. Int J Surg 2011;9:113-116.
Arlotti M, Grossi P, Pea F, Tomei G, Vullo V, De Rosa FG, et al. Consensus document on controversial issues for the treatment of infections of the central nervous system: bacterial brain abscesses. Int J Infect Dis 2010;14 Suppl 4:S79-92.
Lakshmi V, Umabala P, Anuradha K, Padmaja K, Padmasree C, Rajesh A, et al. Microbiological spec- trum of brain abscess at a tertiary care hospital in South India: 24-year data and review. Patholog Res Int 2011;2011:583139.
| Files | ||
| Issue | Vol 8 No 2 (2016) | |
| Section | Articles | |
| Keywords | ||
| GENbag anaer trauma otitis media cyanotic heart disease | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
