Emergence of new lineage of Dengue virus 3 (genotype III) in Lucknow, India
-
Sanjeev Kumar Tripathi
,
Prashant Gupta
,
Vineeta Khare
,
Animesh Chatterjee
,
Rashmi Kumar
,
Mohammed-Yahiya Khan
,
Tapan N Dhole
Abstract
Background and Objectives: Dengue has re-emerged as an important arboviral disease causing significant morbidity. It has become hyperendemic in the Indian subcontinent with all four known dengue serotypes circulating.
Materials and Methods: Multiple sequence alignments and phylogenetic trees of DENV-3 were constructed to determine the extent of the isolated dengue virus genetic heterogeneity and phylogeny.
Results: Sequencing and phylogenetic analysis of the C-prM gene junction revealed an active circulation of a new lineage of DENV-3 (genotype III) in this region of India.
Conclusion: Continuous epidemiological surveillance to monitor the incursion and spread of dengue virus genotypes in this region of India is needed.
Phuong H, de Vries PJ, Thai KT, Nga TT Hung Lq, Giao PT, et al. Dengue virus interactions in Vietnam: tip of an iceberg. Dengue Bull 2006; 30: 15-25.
Setiati TE, Wagenaar JF, de Kruif MD, Mairuhu AT, Gorp EC, Soemantri A. Changing epidemiology of changing haemorrhagic fever in Indonesia. Dengue Bull 2006; 30: 1-14.
Halstead SB. Pathogenesis of dengue: challenges to molecular biology. Science 1988; 239: 476-481.
Monath TP.Dengue: the risk to developed and developing countries. Proc Natl Acad Sci USA 1994; 91: 2395-2400.
Clarke T. Dengue virus: break-bone fever. Nature 2002;416: 672-674.
Gubler DJ. Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century. Trends Microbiol 2002; 10: 100-103.
Holmes EC, Burch SS. The causes and consequences of genetic variation in dengue virus. Trends Microbiol 2000; 8: 74-77.
Wang E, Ni H, Xu R, Barrett AD, Watowich SJ, Gubler DJ, Weaver SC. Evolutionary relationships of endemic/ epidemic and sylvatic dengue viruses. J Virol 2000; 74:3227-3234.
Holmes EC, Twiddy SS. The origin, emergence and evolutionary genetics of dengue virus. Infect Genet Evol 2003; 3: 19-28.
Rico-Hesse R. Microevolution and virulence of dengue viruses. Adv Virus Res 2003; 59: 315-41.
Dash PK, Parida MM, Saxena P, Abhyankar A, Singh CP, Tewari KN, Jana AM, Sekhar K, Rao PV. Reemergence of dengue virus type-3 (subtype-III) in India: implications for increased incidence of DHF & DSS. Virol J 2006; 3: 55-64.
Dash PK, Parida MM, Saxena P, Kumar M, Rai A, Pasha ST, Jana AM. Emergence and continued circulation of dengue-2 (genotype IV) virus strains in northern India. J Med Virol 2004; 74: 314-322.
Singh UB, Seth P. Use of nucleotide sequencing of the genomic cDNA fragments of the capsid/premembrane junction region for molecular epidemiology of dengue type 2 viruses. Southeast Asian J Trop Med Public Health 2001; 32: 326-335.
Dash PK, Saxena P, Abhyankar A, Bhargava R, Jana AM. Emergence of dengue virus type-3 in northern India. Southeast Asian J Trop Med Public Health 2005; 36: 370-377.
Kumar M, Pasha ST, Mittal V, Rawat DS, Arya SC, Agarwal N, et al. Unusal emergence of guate 98-like molecular subtype of DEN-3 during 2003 dengue outbreak in Delhi. Dengue Bull 2004; 28: 161-167.
Gupta P, Khare V, Tripathi S, Nag VL, Kumar R, Khan MY, et al. Assessment of World Health Organization definition of dengue hemorrhagic fever in North India. J Infect Dev Ctries 2010; 4: 150-155.
Tripathi S, Khare V, Gupta P, Chatterjee A, Khan MY, Kumar R, Dhole TN. Sequencing and phylogeny of dengue virus serotype 1 circulating in Lucknow, India. Arch Clin Microbiol 2012; 3: 120-127.18. Yamada K, Takasaki T, Nawa M, Kurane I. Virus isolation as one of the diagnostic methods for dengue virus infection. J Clin Virol 2002; 24: 203-209.
Saxena P, Dash PK, Santhosh SR, Shrivastava A, Parida M, Rao PL. Development and evaluation of one step single tube multiplex RT-PCR for rapid detection and typing of dengue viruses. Virol J 2008; 5: 20.
Hall TA. BioEdit: a user friendly biological sequence alignment editor and analysis program for WINDOWS 95/98/NT. Nucleic Acids Symp Ser 1999; 41: 95-98.
Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994; 22: 4673-4680.
Kumar S, Tamura K, Nei M. MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform 2004; 5: 150-163.
Saitou N, Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 1987; 4: 406-425.
Forattini OP. Epidemiology and phylogenetic relation- ships of dengue viruses. Dengue Bull 2003; 27: 91-94.
Singh UB, Maitra A, Broor S, Rai A, Pasha ST, Seth P.Partial nucleotide sequencing and molecular evolution of epidemic causing Dengue 2 strains. J Infect Dis 1999;180: 959-965.
Kukreti H, Mittal V, Chaudhary A, Rautela RS, Kumar M, Chauhan S, et al.. Continued persistence of a single genotype of dengue virus type-3 (DENV-3) in Delhi, India since its re-emergence over the last decade. J Microbiol Immunol Infect. 2010; 43: 53-61.
Kukreti H, Chaudhary A, Rautela RS, Anand R, Mittal V, Chhabra M, et al. Emergence of an independent lineage of dengue virus type 1 (DENV-1) and its co-circulation with predominant DENV-3 during the 2006 dengue fever outbreak in Delhi. Int J Infect Dis 2008; 12: 542-549.
Bharaj P, Chahar HS, Pandey A, Diddi K, Dar L, Guleria R, et al. Concurrent infections by all four dengue virus serotypes during an outbreak of dengue in 2006 in Delhi, India. Virol J 2008; 5: 1.29. Singh UB, Seth P. Use of nucleotide sequencing of the genomic cDNA fragments of the capsid/premembrane junction region for molecular epidemiology of dengue type 2 viruses. Southeast Asian J Trop Med Public Health 2001; 32: 326-335.
Messer WB, Gubler DJ, Harris E, Sivananthan K, de Silva AM. Emergence and global spread of a dengue serotype 3, subtype III virus. Emerg Infect Dis 2003; 9:800-809.
| Files | ||
| Issue | Vol 5 No 1 (2013) | |
| Section | Articles | |
| Keywords | ||
| Dengue virus genotype III phylogenetic analysis | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
