Tehran University of Medical Sciences Iranian Journal of Microbiology 2008-3289 5 1 2013 03 15 68 75 EN Sanjeev Kumar Tripathi Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India. Prashant Gupta Department of Microbiology, King George Medical University, Lucknow, India. Vineeta Khare Department of Microbiology, Hind Institute of Medical Sciences, Barabanki, India. Animesh Chatterjee Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India. Rashmi Kumar Department of Pediatrics, King George Medical University, Lucknow, India. Mohammed-Yahiya Khan Department of Biotechnology, Babasahib Bhimrao Ambedkar University, Lucknow, India. Tapan N Dhole Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India. 2015 10 16 Background and Objectives: Dengue has re-emerged as an important arboviral disease causing significant morbidity. It has become hyperendemic in the Indian subcontinent with all four known dengue serotypes circulating. Materials and Methods: Multiple sequence alignments and phylogenetic trees of DENV-3 were constructed to determine the extent of the isolated dengue virus genetic heterogeneity and phylogeny. Results: Sequencing and phylogenetic analysis of the C-prM gene junction revealed an active circulation of a new lineage of DENV-3 (genotype III) in this region of India. Conclusion: Continuous epidemiological surveillance to monitor the incursion and spread of dengue virus genotypes in this region of India is needed. https://ijm.tums.ac.ir/index.php/ijm/article/view/655 https://ijm.tums.ac.ir/index.php/ijm/article/download/655/427