Case Report

Diagnostic insights into disseminated histoplasmosis: a case report highlighting bone marrow analysis

Abstract

We present a case of a 43-year-old immunocompromised female patient diagnosed with disseminated histoplasmosis on bone marrow examination, at clinical laboratory of Kasturba Hospital, Manipal, Karnataka, India. The patient, presenting with symptoms like weight loss, appetite loss, and pancytopenia, underwent bone marrow aspiration and biopsy. The bone marrow studies revealed HIV-associated changes and the yeast form of Histoplasma capsulatum, confirming disseminated histoplasmosis. Bone marrow examination is highlighted as a diagnostic tool with significant sensitivity in such cases. The report stresses on the importance of awareness and early diagnosis of histoplasmosis in immunocompromised patients, given its potential lethality and the need for timely therapeutic intervention for better prognosis.

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Files
IssueVol 16 No 1 (2024) QRcode
SectionCase Report(s)
DOI https://doi.org/10.18502/ijm.v16i1.14886
Keywords
Histoplasmosis; HIV infection; Opportunistic infection; Pancytopenia; Bone marrow examination
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Kaushik V, Khanna R, Khanna V, Varma M. Diagnostic insights into disseminated histoplasmosis: a case report highlighting bone marrow analysis. Iran J Microbiol. 2024;16(1):155-158.