Prevalence and capsular type distribution of group B Streptococcus isolated from vagina of pregnant women in Nghe An province, Vietnam

  • Tran Quang Hanh Department of Obstetrics, Nghe An Obstetrics and Pediatrics Hospital, Nghe An, Vietnam
  • Vu Van Du Department of Treatment on Demand, National Hospital of Obstetrics and Gynecology, Hanoi, Vietnam
  • Pham Thu Hien Department of Treatment on Demand, National Hospital of Pediatrics, Hanoi, Vietnam
  • Duong Dinh Chinh Department of Neurology, Nghe An Friendship General Hospital, Nghe An, Vietnam
  • Cao Ba Loi Department of Science and Training, National Institute of Malaria Parasitology and Entomology, Hanoi, Vietnam
  • Nguyen Manh Dung Department of Anesthesiology and Critical Care, 108 Military Centre Hospital, Hanoi, Vietnam
  • Do Ngoc Anh Mail Department of Medical Parasitology, Military Medical University, Hanoi, Vietnam
  • Tran Thi Kieu Anh Department of Paediatric, Vinh Medical University, Nghe An, Vietnam
Keywords:
Group B Streptococcus, Prevalence, Serotypes, Nghe An, Vietnam

Abstract

Background and Objectives: Identification of GBS serotypes provides helpful information for appropriate the development of suitable vaccines; however, no reports from Vietnam have been published. This study has been performed to find the prevalence and serotypes of group B Streptococcus isolated from vagina of pregnant women in Nghe An province, Vietnam.
Materials and Methods: Vaginal swabs were collected from pregnant women at 35-37 weeks of gestation at the Nghe An Obstetrics and Pediatrics Hospital, Vietnam between May 2018 and July 2019. The swabs were cultured on 5% sheep blood agar for isolation of GBS. All isolates were identified using the Gram staining, CAMP test and specific PCR. GBS strains were serotyped using the multiplex PCR assays.
Results: The prevalence of vaginal GBS colonization was 9.20% of 750 participants. Among the isolates, serotypes III (39.13%) and V (31.89%) were the most frequent, followed by serotypes Ia (11.59%), VI (11.59%), Ib (2.90%), II (1.45%) and VII (1.45%), respectively. Serotypes IV, VIII and IX were not found.
Conclusion: The prevalence of GBS in the Nghe An province of central Vietnam was similar to reports from other parts of the world. The predominat GBS serotypes (III, V, Ia and VI) were slightly different from those previously described from other regions around the world. The high frequency of serotype VI was a notable feature of the strains from pregnant women in Vietnam.

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Published
2020-03-02
How to Cite
1.
Hanh T, Du V, Hien P, Chinh D, Loi C, Dung N, Anh D, Anh TT. Prevalence and capsular type distribution of group B Streptococcus isolated from vagina of pregnant women in Nghe An province, Vietnam. Iran J Microbiol. 12(1):11-17.
Section
Original Article(s)