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Catalase-negative Staphylococcus aureus isolated from a diabetic foot ulcer

Abstract

We report a catalase-negative Staphylococcus aureus isolated from a 56-year-old male diabetic patient with foot ulcer who attended our surgery ward. Species identification was confirmed by Gram staining, standard biochemical tests and PCR amplification of the nuc and fem genes. Antibiotic susceptibility showed that the strain was sensitive to imepenem, chloramphenicol, amoxicillin, vancomycin and resistant to oxacillin, penicillin, ceftriaxone, erythromycin, clindamycin, and amikacin. Clinicians and microbiologists must be encouraged to identify and report these atypical strains and the infections associated with them in order to establish their role in pathogenesis.

BM Gruner, SR Han , HG Meyer, U Wulf , S Bhakdi and EK Siegel. Characterization of a Catalase-Negative Methicillin-Resistant Staphylococcus aureus strain. J Clin Microbiol 2007; 1: 2684-2685.

WE Kloos and TL Bannerman. In: Murray PR et al, Eds. Staphylococcus and Micrococcus. Manual of clinical microbiology, 7th ed. ASM Press, Washington, DC.1999; 264- 282.

R Sanz, I Marn, JA Ruiz-Santa-Quiteria , JA Orden, D Cid, RM Diez , et al. Catalase deficiency in Staphylococcus aureus subsp. anaerobius is associated with natural loss-of-function mutations within the structural gene. Microbiology 2000; 146: 465-475.

X Bertrand, Y ves Hugueninb, D Talona. First report of a catalase-negative methicillin-resistant Staphalococcus aureus. Diagn Microbiol Infect Dis 2002; 43: 245-246.

AO Shittu1, J Lin , D Morrison, DO Kolawole. Isolation and Molecular Confirmation of a Multiresistant Catalase- negative Staphylococcus aureus in Nigeria. J Infect 2003; 46: 203-205.

PA Wayne. Performance Standards for Antimicrobial Disk Susceptibility Tests. NCCLS document M2-A7. National Committee for Clinical Laboratory Standards. NCCLS. 2000.

Maraki S, Stylianoudaki E, Nioti E, Tselentis Y. Catalase- negative Staphylococcus aureus wounds infection: Case report and review. Clin Microbiol Newsletter 2005; 27:175-177.

Mandell GL. Catalase, superoxide dismutase, and virulence of Staphylococcus aureus in vitro and in vivo studies with emphasis on Staphylococcal-leukocyte interaction. J Clin Invest 1975; 55: 561-566.

Friedberg B, Hauer E, Belkhirat M, Watine J, Le Coustumier A. Catalase-negative Staphylococcus aureus: a rare cause of catheter-related bacteremia. Clin Microbiol Infect 2003; 9: 1253-1255.

Yilmaz M, Aygun G, Utku T, Dikmen Y, Ozturk R.First report of catalase-negative methicillin-resistant Staphylococcus aureus sepsis. J Hosp Infect 2005; 60:188-189.

Tu KK, Palutke WA. Isolation and characterization of a catalase-negative strain of Staphylococcus aureus. J Clin Microbiol 1976; 3: 77-78.

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IssueVol 2 No 3 (2010) QRcode
SectionArticles
Keywords
Diabetes Mellitus Diabetic Foot Staphylococcus aureuS

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How to Cite
1.
Dezfulian A, Salehian M, Amini V, Dabiri H, Azimirad M, Aslani M, Zali M, Fazel I. Catalase-negative Staphylococcus aureus isolated from a diabetic foot ulcer. Iran J Microbiol. 1;2(3):165-167.