Heavy hearts: the impact of influenza on young lives, a rare case report
-
Uksim Qadri
,
Sanam Wani
,
Saleem Javaid Wani
,
Bashir Ahmad Fomda
,
Umaya Majid
,
Iram Jan
,
Suraiya Mir
Abstract
Considerable information is available about the acute respiratory symptoms of influenza A and B. However, rarely, these viruses can adversely affect the cardiovascular system. Few cases of pericardial effusion and cardiac tamponade due to the Influenza virus have been reported. To the best of our knowledge, we present the first case of a 23-year-old unvaccinated woman having concurrent influenza A and B infection manifesting as pericardial effusion and cardiac tamponade. The patient was treated with oseltamivir 75 mg, resulting in significant clinical improvement. This case emphasizes the importance of considering influenza as a possible cause of cardiac tamponade.
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13. Radovanovic M, Dumic I, Nordstrom CW, Hanna RD. Fulminant influenza A myocarditis complicated by transient ventricular wall thickening and cardiac tamponade. Infect Dis Rep 2022; 14: 600-608.
14. Sidhu RS, Sharma A, Paterson ID, Bainey KR. Influenza H1N1 infection leading to cardiac tamponade in a previously healthy patient: A case report. Res Cardiovasc Med 2016; 5(3): e31546.
15. Monto AS, Gravenstein S, Elliott M, Colopy M, Schweinle J. Clinical signs and symptoms predicting influenza infection. Arch Intern Med 2000; 160: 3243-3247.
16. Schroff P, Hovey JR, Tharumia Jagadeesan C, Nagalapuram V, Chaucer B. Cardiac Tamponade secondary to Influenza B infection. Cureus 2021; 13(5): e14888.
17. Desai R, Jain A, Singh S, Raina J, Itare V, Shivakumar J, et al. Postinfluenza cardiac Tamponade: A review of published case reports. SN Compr Clin Med 2023; 5: 64.
18. Chughtai AA, Tan TC, Hitchen EM, Kunasekaran M, MacIntyre CR. Association of influenza infection and vaccination with cardiac biomarkers and left ventricular ejection fraction in patients with acute myocardial infarction. Int J Cardiol Heart Vasc 2020; 31: 100648.
2. Kytö V, Sipilä J, Rautava P. Clinical profile and influences on outcomes in patients hospitalized for acute pericarditis. Circulation 2014; 130: 1601-1606.
3. Maisch B, Seferović PM, Ristić AD, Erbel R, Rienmüller R, Adler Y, et al. Guidelines on the diagnosis and management of pericardial diseases executive summary; The Task force on the diagnosis and management of pericardial diseases of the European society of cardiology. Eur Heart J 2004; 25: 587-610.
4. Seferović PM, Ristić AD, Maksimović R, Simeunović DS, Milinković I, Seferović Mitrović JP, et al. Pericardial syndromes: an update after the ESC guidelines 2004. Heart Fail Rev 2013; 18: 255-266.
5. Gouriet F, Levy PY, Casalta JP, Zandotti C, Collart F, Lepidi H, et al. Etiology of pericarditis in a prospective cohort of 1162 cases. Am J Med 2015; 128: 784.e1-8.
6. Imazio M, Gaita F, LeWinter M. Evaluation and treatment of pericarditis: a systematic review. JAMA 2015; 314: 1498-1506.
7. Sellers SA, Hagan RS, Hayden FG, Fischer WA 2nd. The hidden burden of influenza: A review of the extra-pulmonary complications of influenza infection. Influenza Other Respir Viruses 2017; 11: 372-393.
8. Mamas MA, Fraser D, Neyses L. Cardiovascular manifestations associated with influenza virus infection. Int J Cardiol 2008; 130: 304-309.
9. Institute of Medicine (US) forum on Microbial Threats. The threat of Pandemic Influenza: are we ready? Workshop Summary. Knobler SL, Mack A, Mahmoud A, Lemon SM, editors. Washington (DC): National Academies Press (US); 2005.
10. Madjid M, Aboshady I, Awan I, Litovsky S, Casscells SW. Influenza and cardiovascular disease: Is there a causal relationship? Tex Heart Inst J 2004; 31: 4-13.
11. Nguyen JL, Yang W, Ito K, Matte TD, Shaman J, Kinney PL. Seasonal influenza infections and cardiovascular disease mortality. JAMA Cardiol 2016; 1: 274-281.
12. Rezkalla SH, Kloner RA. Influenza-related viral myocarditis. WMJ 2010; 109: 209-213.
13. Radovanovic M, Dumic I, Nordstrom CW, Hanna RD. Fulminant influenza A myocarditis complicated by transient ventricular wall thickening and cardiac tamponade. Infect Dis Rep 2022; 14: 600-608.
14. Sidhu RS, Sharma A, Paterson ID, Bainey KR. Influenza H1N1 infection leading to cardiac tamponade in a previously healthy patient: A case report. Res Cardiovasc Med 2016; 5(3): e31546.
15. Monto AS, Gravenstein S, Elliott M, Colopy M, Schweinle J. Clinical signs and symptoms predicting influenza infection. Arch Intern Med 2000; 160: 3243-3247.
16. Schroff P, Hovey JR, Tharumia Jagadeesan C, Nagalapuram V, Chaucer B. Cardiac Tamponade secondary to Influenza B infection. Cureus 2021; 13(5): e14888.
17. Desai R, Jain A, Singh S, Raina J, Itare V, Shivakumar J, et al. Postinfluenza cardiac Tamponade: A review of published case reports. SN Compr Clin Med 2023; 5: 64.
18. Chughtai AA, Tan TC, Hitchen EM, Kunasekaran M, MacIntyre CR. Association of influenza infection and vaccination with cardiac biomarkers and left ventricular ejection fraction in patients with acute myocardial infarction. Int J Cardiol Heart Vasc 2020; 31: 100648.
| Files | ||
| Issue | Vol 17 No 3 (2025) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/ijm.v17i3.18834 | |
| Keywords | ||
| Cardiac tamponade Influenza A and B virus coinfection Pericardial effusion Viral cardiomyopathies | ||
| Rights and permissions | |
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Qadri U, Wani S, Wani S, Fomda B, Majid U, Jan I, Mir S. Heavy hearts: the impact of influenza on young lives, a rare case report. Iran J Microbiol. 2025;17(3):511-515.
