Effect of iron and silver nanoparticles on coenzyme Q10 production by Gluconobacter japonicus FM10
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Abstract
Background and Objectives: Coenzyme Q10 is an anti-aging agent whose demand is increasing progressively. There are various strategies used for increasing coenzyme Q10 production by microorganisms. In this study, for the first time, we investigated the effect of iron oxide and silver nanoparticles on coenzyme Q10 production by Gluconobacter japonicus FM10.
Materials and Methods: In the first step, a preliminary experiment was set and carried out to obtain the minimum inhibitory concentrations of the nanoparticles on the strain FM10. Then the sub-MIC concentrations were used to investigate their effect on coenzyme Q10 production in the stationary and exponential phases of the growth, separately.
Results: The results showed that coenzyme Q10 production increased in the presence of the iron oxide and silver nanoparticles. The silver nanoparticles induced 1.9 times higher coenzyme Q10 production. The highest level of coenzyme Q10 was induced when the silver nanoparticles were added to the culture medium at the stationary phase.
Conclusion: This should be noticed that so far nanoparticles have been considered as antibacterial agents, rather than being considered to cause probable beneficial effects on the induction of useful products in the microbial world. In this regard, their potential for increasing coenzyme Q10 production has received no attention. However, our present results showed that the nanoparticles can be used to increase the production efficiency of coenzyme Q10 in Gluconobacter.
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18. Sondi I, Salopek-Sondi B. Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram negative bacteria. J Colloid Interface Sci 2004; 275: 177-182.
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21. Ghasemi B, Hosseini R, Dehghan F. Effect of cobalt nanoparticles on artemisinin production and gene expression in Artemisia annua. Turk J Bot 2015;39:769-777.
22. Ghanati F, Bakhtiarian S. Effect of methyl jasmonate and silver nanoparticles on production of secondary metabolites by Calendula officinalis L (Asteraceae). Trop J Pharm Res 2014; 13: 1783-1789.
23. Zhang B, Zheng LP, Li WY, Wang JW. Stimulation of artemisinin production in Artemisia annua hairy roots by Ag-SiO2 core-shell nanoparticles. Curr Nanosci 2013; 9: 363-370.
24. Alamdar N, Rasekh B, Yazdian F. The effect of nanoparticles on the biosurfactant production by Pseudomonas aeruginosa for use in the oil industry. JMBS 2019; 10: 223-229.
25. Liu J, Vipulanandan C, Cooper TF, Vipulanandan G. Effects of Fe nanoparticles on bacterial growth and biosurfactant production. J Nanopart Res 2013; 15: 1405.
26. Jalili M, Emtiazi G. The effect of nanoparticles and organic acids on bacterial nanocellulose synthesis, crystalline structure and water holding capacity. Adv Res Microb Metab Technol 2018; 1: 1-11.
27. Hou J, Miao L, Wang C, Wang P, Ao Y, Lv B. Effect of CuO nanoparticles on the production and composition of extracellular polymeric substances and physicochemical stability of activated sludge flocs. Bioresour Technol 2015; 176: 65-70.
28. Sahebnazar Z, Mowla D, Karimi G. Enhancement of Pseudomonas aeruginosa growth and rhamnolipid production using iron-silica nanoparticles in low-cost medium. J Nanostruct 2018; 8: 1-10.
29. Kiran GS, Nishanth LA, Priyadharshini S, Anitha K, Selvin J. Effect of Fe nanoparticle on growth and glycolipid biosurfactant production under solid state culture by marine Nocardiopsis sp. MSA13A. BMC Biotechnol 2014; 14:48.
30. Choi GS, Kim YS, Seo JH, Ryu YW. Restricted electron flux increases coenzyme Q10 production in Agrobacterium tumefaciens ATCC4452. Process Biochem 2005; 40: 3225-3229.
31. Costa CS, Vieira Ronconi JV, Felipe Daufenbach J, Gonçalves CL, Tezza Rezin G. In vitro effects of silver nanoparticles on the mitochondrial respiratory chain. Mol Cell Biochem 2010; 342: 51-56.
32. Manke A, Wang L, Rojanasakul Y. Mechanisms of nanoparticle-induced oxidative stress and toxicity. Biomed Res Int 2013; 2013:942916.
33. Ha SJ, Kim SY, Seo JH, Oh DK, Jeya M. Ca2+ increase the specific coenzyme Q10 content in Agrobacterium tumefaciens. Bioprocess Biosyst Eng 2009; 32: 697-700.
34. Cameron SJ, Hosseinian F, Willmore WG. A current overview of the biological and cellular effects of nanosilver. Int J Mol Sci 2018; 19: 2030.
2. Cluis CP, Burja AM, Martin VJJ. Current prospects for the production of coenzyme Q10 in microbes. Trends Biotechnol 2007; 25: 514-521.
3. Turunen M, Olsson J, Dallner G. Metabolism and function of coenzyme Q10. Biochim Biophys Acta 2004; 1660: 171-199.
4. Kapoor P, Kapoor Kh. Coenzyme Q10-a novel molecule. J Indian Acad Clin Med 2013; 14: 37-45.
5. Ndikubwimana JD, Lee BH. Enhanced production techniques, properties and uses of coenzyme Q10. Biotechnol Lett 2014; 36: 1917-1926.
6. Bentinger M, Tekle M, Dallner G. Coenzyme Q10- biosynthesis and functions. Biochem Biophys Res Commun 2010; 396: 74-79.
7. Choi JH, Ryu YW, Seo JH. Biotechnological production and applications of coenzyme Q10. Appl Microbiol Biotechnol 2005; 68: 9-15.
8. Cluis CP, Pinel D, Martin VJ. The production of coenzyme Q10 in microorganisms. Subcell Biochem 2012; 64: 303-326.
9. Gupta A, Singh VK, Qazi GN, Kumar A. Gluconobacter oxydans: Its biotechnological applications. J Mol Microbiol Biotechnol 2001; 3: 445-456.
10. Gomes RJ, Borges MF, Rosa MF, Castro-Gómez RJH, Spinosa WA. Acetic acid bacteria in the food industry: systematics, characteristics and applications. Food Technol Biotechnol 2018;56:139-151.
11. Bringer S, Bott M (2016). Central Carbon Metabolism and Respiration in Gluconobacter oxydans. In: Acetic Acid Bacteria: Ecology & Physiology. Eds, K Matsushita, H Toyama, N Tonouchi, A Okamoto-Kainuma. Springer Publishing, Tokyo, Japan, pp. 235-253.
12. Adachi O, Moonmangmee D, Toyama H, Yamada M, Shinagawa E. New development in oxidative fermentation. Appl Microbiol Biotechnol 2003; 60: 643-653.
13. Adachi O, Yakushi T (2016). Membrane-bound dehydrogenases of acetic acid bacteria. In: Acetic Acid Bacteria: Ecology & Physiology. Eds, K Matsushita, H Toyam, N Tonouchi,A Okamoto-Kainuma. Springer Publishing, Tokyo, Japan, pp. 273-294.
14. Moghadami F, Fooladi J, Hosseini R. Introducing a thermotolerant Gluconobacter japonicus strain, potentially useful for coenzyme Q10 production. Folia Microbiol (Praha) 2019; 64:471-479.
15. Sanchooli N, Saidi S, Khandan H, Sanchooli E. In vitro antibacterial effects of silver nanoparticles synthesized using Verbena officinalis leaf extract on Yersinia ruckeri, Vibrio cholera and Listeria monocytogenes. Iran J Microbiol 2018; 10: 400-408.
16. Hajipour M, Fromm K, Ashkarran A, Aberasturi D, Larramendi I, Rojo T, et al. Antibacterial properties of nanoparticles. Trends Biotechnol 2012; 30: 499-511.
17. Elkomy RG. Antimicrobial screening of silver nanoparticles synthesized by marine cyanobacterium Phormidium formosum. Iran J Microbiol 2020; 12: 242-248.
18. Sondi I, Salopek-Sondi B. Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram negative bacteria. J Colloid Interface Sci 2004; 275: 177-182.
19. Subbiahdoss G, Sharifi S, Grijpma DW, Laurent S, van der Mei HC, Mahmoudi M, et al. Magnetic targeting of surface-modified superparamagnetic iron oxide nanoparticles yields antibacterial efficacy against biofilms of gentamicin-resistant staphylococci. Acta Biomater 2012; 8: 2047-2055.
20. Garsia-Ruiz, Crespo J, Lopez-de-Luzuriaga J, Olmos M, Monge M, et al. Novel biocompatible silver nanoparticles for controlling the growth of lactic acid bacteria and acetic acid bacteria in wines. Food Control 2015; 50: 613-619.
21. Ghasemi B, Hosseini R, Dehghan F. Effect of cobalt nanoparticles on artemisinin production and gene expression in Artemisia annua. Turk J Bot 2015;39:769-777.
22. Ghanati F, Bakhtiarian S. Effect of methyl jasmonate and silver nanoparticles on production of secondary metabolites by Calendula officinalis L (Asteraceae). Trop J Pharm Res 2014; 13: 1783-1789.
23. Zhang B, Zheng LP, Li WY, Wang JW. Stimulation of artemisinin production in Artemisia annua hairy roots by Ag-SiO2 core-shell nanoparticles. Curr Nanosci 2013; 9: 363-370.
24. Alamdar N, Rasekh B, Yazdian F. The effect of nanoparticles on the biosurfactant production by Pseudomonas aeruginosa for use in the oil industry. JMBS 2019; 10: 223-229.
25. Liu J, Vipulanandan C, Cooper TF, Vipulanandan G. Effects of Fe nanoparticles on bacterial growth and biosurfactant production. J Nanopart Res 2013; 15: 1405.
26. Jalili M, Emtiazi G. The effect of nanoparticles and organic acids on bacterial nanocellulose synthesis, crystalline structure and water holding capacity. Adv Res Microb Metab Technol 2018; 1: 1-11.
27. Hou J, Miao L, Wang C, Wang P, Ao Y, Lv B. Effect of CuO nanoparticles on the production and composition of extracellular polymeric substances and physicochemical stability of activated sludge flocs. Bioresour Technol 2015; 176: 65-70.
28. Sahebnazar Z, Mowla D, Karimi G. Enhancement of Pseudomonas aeruginosa growth and rhamnolipid production using iron-silica nanoparticles in low-cost medium. J Nanostruct 2018; 8: 1-10.
29. Kiran GS, Nishanth LA, Priyadharshini S, Anitha K, Selvin J. Effect of Fe nanoparticle on growth and glycolipid biosurfactant production under solid state culture by marine Nocardiopsis sp. MSA13A. BMC Biotechnol 2014; 14:48.
30. Choi GS, Kim YS, Seo JH, Ryu YW. Restricted electron flux increases coenzyme Q10 production in Agrobacterium tumefaciens ATCC4452. Process Biochem 2005; 40: 3225-3229.
31. Costa CS, Vieira Ronconi JV, Felipe Daufenbach J, Gonçalves CL, Tezza Rezin G. In vitro effects of silver nanoparticles on the mitochondrial respiratory chain. Mol Cell Biochem 2010; 342: 51-56.
32. Manke A, Wang L, Rojanasakul Y. Mechanisms of nanoparticle-induced oxidative stress and toxicity. Biomed Res Int 2013; 2013:942916.
33. Ha SJ, Kim SY, Seo JH, Oh DK, Jeya M. Ca2+ increase the specific coenzyme Q10 content in Agrobacterium tumefaciens. Bioprocess Biosyst Eng 2009; 32: 697-700.
34. Cameron SJ, Hosseinian F, Willmore WG. A current overview of the biological and cellular effects of nanosilver. Int J Mol Sci 2018; 19: 2030.
| Files | ||
| Issue | Vol 12 No 6 (2020) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/ijm.v12i6.5034 | |
| Keywords | ||
| Coenzyme Q10; Gluconobacter; Nanoparticles; Exponential phase; Stationary phase | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Moghadami F, Hosseini R. Effect of iron and silver nanoparticles on coenzyme Q10 production by Gluconobacter japonicus FM10. Iran J Microbiol. 2020;12(6):592-600.
