Prevalence of Mycobacterium tuberculosis in the samples referred to the tuberculosis research laboratory in Mashhad Ghaem Hospital during 2005-2006
,
Abstract
Background: Tuberculosis continues to be a serious public health problem causing nearly three million deaths per year all over the world. Despite major improvement in diagnosis, it is not possible to control the disease in the absence of surveillance treatment, and follow-up programs.
Objectives: This research was designed to study the frequency of Mycobacterium tuberculosis among specimens referred to the tuberculosis research laboratory in Qaem Hospital, Mashhad, North- East of Iran in 2005-2006.
Materials and Methods: 3207 samples (1331 sputum, 1209 bronchial lavage, 69 ascitis aspirates, 52 urine samples, 30 CSF samples, 25 joint aspirates and 15 wound secretions) were cultured according to standard procedure and examined microscopi- cally using Ziehl Neelsen staining method.
Results: 536 samples (16.7%) recognized as positive for Mycobacterium tuberculosis. (bronchial lavage 18.6%, sputum 17%, gastric lavage 13.3%, CSF 10%, ascitis aspirates 7.2%, wound 6.25%, pleural aspiration 4.5%). No Mycobacterium tubercu- losis was found in urine samples and joint aspirates.
Conclusion: Considering reported prevalence of 13 cases per 100,000 in the Iranian population, these results are acceptable but more preventive measures should be sought for controlling TB.
Dye C, Scheele S, Dolin P, Pathania V, Raviglione MC.Global burden of tuberculosis- estimated incidence, Prevalence, and Mortality by Country. JAMA 1999;282: 677– 686.
Rajeswari R, Balasubramanian R, Muniyandi M, Geetharamani S, Thresa X, Venkatesan P. Socio- economic impact of tuberculosis on patients and family in India. Int J Tuberc Lung Dis 1999; 3:869–877.
Sundre P, ten Dam G, Kochi A. Tuberculosis: a global overview of the situation today. Bull World Health Organ 1992;70:149– 159.
Tabbara KF. Tuberculosis. Curr Opin Ophthalmol 2007;18:493-501.
Alavi SM, Sefidgaran GH. Tuberculin survey among school-aged children in Ahvaz, Iran, 2006. Int J Infect Dis 2008 ;12:406- 409.
Raviglione MC, Dye C, Schmidt S, Kochi A. Assessment of worldwide tuberculosis controls. Lancet 1997; 350:624- 629.
Shinnick T, Good R. Diagnostic mycobacteriology laboratory practices. Clin Infect Dis. 1995;21: 291-299.
James LV.Mycobacterium tuberculosis and other nontuberculosis mycobacteria. In: Connie R. Mahon, George Manuselis, Donald C. Lehman, editors. Textbook of Diagnostic Microbiology. Philadelphia: W.B. Saunders Company. 2000; pp 669-707.
Rieder HL, Martin CT, Myking H, Urbanczik R, Laszlo A Kim SJ et al (1998). The Public Health Service National Tuberculosis Reference Laboratory and the National Laboratory Network: Minimum Requirements, Role and Operation in a Low- Income Country. International Union against Tuberculosis and Lung Disease. Paris, France.
Cho SN, Brennan PJ. Tuberculosis: diagnostics.Tuberculosis (Edinb). 2007; Suppl 1:S14-7.
World Health Organization. Global Tuberculosis Pro- gram. Global Tuberculosis Control. WHO (1999), Geneva.
Global Facts about TB from “ Global Tuberculosis control: WHO Report, 2000 ”. ( http://www.who-int/).
Long R, Njoo H, Hershfield E. Tuberculosis: Epidemiology of the disease in Canada. CMAJ 1999;160: 185-1190.
Dolin PJ, Raviglione MC, Kochi A. Global tuberculosis incidence and mortality during 1990–2000. Bull World Health Organ 1994; 72: 213-220.
Des Prez RM, Heim CR (2000). Mycobacterium tuberculosis. In: Mandell GL, Bennett JE, Dolin R, Eds. Principles and practice of infectious diseases. Philadelphia: Churchill Livingstone, pp. 1877-1906.
Hussain H, Akhtar S, Nanan D. Prevalence of and risk factors associated with Mycobacterium tuberculosis infection in prisoners, North West Frontier Province, Pakistan. Int J Epidemiol 2003;32: 794-799.
Tupasi TE, Radhakrishna S, Quelapio MI, Villa ML, Pa- scual ML, Rivera AB, et al. Tuberculosis in the urban poor settlements in the Philippines. Int J Tuberc Lung Dis 2000; 4:4-11.
Śanchez- Pérez HJ, Flores- Hernández JA, J a n s á J M , Caylá JA, Martín- Mateo M. Pulmonary tuberculosis and associated factors in areas of high levels of poverty in Chiapas, Mexico. Int J Epidemiol 2001;30:386-393.
| Files | ||
| Issue | Vol 1 No 3 (2009) | |
| Section | Articles | |
| Keywords | ||
| Mycobacterium tuberculosis Ziehl Neelsen staining prevalence | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
