A severe Morganella morganii endophthalmitis; followed by bacteremia
Abstract
Morganella morganii is rarely isolated from nosocomial infections. However, postoperative infections due to Morganella spp. were documented in literature and eye involvements of the infections usually result in severe sequels. We present a severe case infection, which was caused by M. morganii subsp. morganii, firstly appearing as conjunctivitis and complicated by bacteremia. The infectious agent isolated from both conjunctival and consecutive blood cultures. Identification and anti- microbial susceptibility tests were performed with the Vitek 2® automated system. The isolate was resistant to cephalosporins and carbapenems and it had ability to produce extended spectrum beta-lactamases. Patient was successfully treated with intravenous ciprofloxacin according to susceptibility test results. This is the first report of M. morganii infection detected as a local infection then complicated by bacteremia.
O'Hara CM, Brenner FW, Miller JM. Classification, identification, and clinical significance of Proteus, Providencia, and Morganella. Clin Microbiol Rev 2000, 13:534-546.
Johnson JR, Feingold M. 1998. Case of chorioamnioni- tis in an immunocompetent woman caused by Morgan- ella morganii. J Matern Fetal Med 1998; 7:13-14.
Salen PN, Eppes S. Morganella morganii, a newly re- ported, rare cause of neonatal sepsis. Acad Emerg Med 1997; 4:711–714.
Sica S, Di Mario A, Salutari P, d'Onofrio G, Antinori A, Chiusolo P, Leone G. Morganella morganii pericar- ditis after resolventsple- nectomy for immune pancyto- penia following allogeneic bone marrow trans- planta- tion for acute lymphoblastic leukemia. Clin Infect Dis 1995; 21:1052– 1053.
Gebhart-Mueller Y, Mueller P, Nixon B. Unusual case of postoperative infection caused by Morganella mor- ganii. J Foot Ankle Surg 1998;37:145–147.
Jensen M, Fiscella R, Crandall A, Moshirfar M,Mooney B, Olson R, et al. Original Article: A retro- spective study of endophtalmitis rates comparing quinolone antibiotics. Am J Of Ophthalmol [serial on the Internet]. (2005, Jan 1), 139: 141-148.
Eifrig CW, Scott IU, Flynn HW, Miller D. Endophthal- mitis caused by Pseudomonas aeruginosa. Ophthal- mology 2003; 110:1714–1717.
Scott IU, Matharoo N, Flynn HW, Miller D. Endoph- thalmitis caused by Klebsiella species. Am J Ophthal- mol 2004;138: 662–663.
Okumoto M, Smolin G, Belfort R, Kim HB, Siverio CE. Proteus species isolated from human eyes. Am J Ophthalmol 1976;81:495–501.
Lee IK, Liu JW. Clinical characteristics and risk fac- tors for mortality in Morganella morganii bacteremia. J Microbiol Immunol Infect 2006;39:328-34.
Poirel L, Girlich D, Nordmann P, Guibert M, Naas T.Cloning, sequence analyses, expression, and distribu- tion of ampC-ampR from Morganella morganii clinical isolates. Antimicrob Agents Chemother 1999;43:769-776.
Flannery EL, Antczak SM, Mobley HL. Self-trans- missibility of the integrative and conjugative element ICEPm1 between clinical isolates requires a functional integrase, relaxase, and Type IV secretion system. J Bacteriol 2011 ;193:4104-4112..
Shi DS, Wang WP, Kuai SG, Shao HF, Huang M. Iden- tification of bla KPC-2 on different plasmids of three Morganella morganii isolates. Eur J Clin Microbiol Infect Dis 2012;31:797-803.
Files | ||
Issue | Vol 8 No 1 (2016) | |
Section | Articles | |
Keywords | ||
Morganella morganii Conjunctivitis Bacteremia Ciprofloxacin |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |