Tehran University of Medical Sciences Iranian Journal of Microbiology 2008-3289 18 4 2026 08 04 Brucellosis-related pancytopenia: a diagnostic and therapeutic challenge case report from an endemic region 633 636 Zahra Jahani Department of Infectious Diseases and Tropical Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Clinical Research Development Unit, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran Zohreh Jahani3 Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran 2025 11 17 2026 07 08 Brucellosis, endemic in the Middle East and similar regions, can present with pancytopenia, complicating diagnosis and treatment. We report a 62-year-old female with fever, fatigue, and weight loss. Persistent pancytopenia required prolonged triple antibiotic therapy. Clinicians must consider brucellosis–related pancytopenia and tailor therapy with careful monitoring. https://ijm.tums.ac.ir/index.php/ijm/article/view/5940 https://ijm.tums.ac.ir/index.php/ijm/article/download/5940/1924