Tehran University of Medical Sciences Iranian Journal of Microbiology 2008-3289 16 2 2024 04 19 201 207 Ananya Arora Department of Microbiology, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Sanjay Biswas Department of Microbiology, Tata Memorial Hospital, Mumbai, India Vandita Pahwa Department of Preventive Oncology, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Naveen Bansal Department of Transfusion Medicine, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Sneha Verghese Department of Nursing, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Nancy Rodrigues Department of Nursing, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Ashish Gulia Department of Surgical Oncology, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Jigeeshu Divatia Department of Anaesthesia, Tata Memorial Hospital, Mumbai, India Rahat Brar Department of Radiodiagnosis, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Sankalp Sancheti Department of Oncopathology, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Charu Singh Department of Microbiology, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India Aman Saxena Department of Microbiology, Homi Bhabha Cancer Hospital and Research Centre, Punjab, India 2023 09 02 2024 02 25 Background and Objectives: Needle stick injury (NSI) is the most dreaded occupational health hazard affecting a healthcare worker (HCW) psychologically and physically. The risk of infection post needle stick injury ranges between 1.9% to greater than 40% for HBV infections, 2.7-10% for HCV and 0.2-0.44% for HIV infections. As per National AIDS Control Organisation (NACO) records, nursing staff is at highest risk (43%) followed by physicians (28%). The main objective of this study was to evaluate knowledge of nursing staff about needle stick injuries and to study factors leading to such incidents in their working areas, impart them knowledge regarding the same and fill gaps in knowledge. Materials and Methods: This is a cross-sectional retrospective analysis involving nursing staff and students. p values were calculated using SPSS software. Results: Overall NSI prevalence among nursing staff and students was 51.6% whereas in more exposed and less exposed group was 47.45% and 10.16% respectively (p=0.2056). The most common cause of NSI incident was recapping of needle (38.5%) followed by transferring needle to sharp container (35%). Conclusion: Consequences of NSI are serious and this study has tried to emphasize on the need to study the factors leading to NSI. https://ijm.tums.ac.ir/index.php/ijm/article/view/4381 https://ijm.tums.ac.ir/index.php/ijm/article/download/4381/1656